Changing motherboard under a Ubuntu box

"I've done radical H/W changes under Ubuntu- for example, switching from Intel/Intel to AMD/nVidia CPU & Chipset, and had it just boot up and work. However,

I had already changed /etc/fstab to use /dev/sd* instead of auto-generated numbers (just BECAUSE), and
I had no RAID of any kind, and
I had an image backup ""just in case"".

If you can sort out your RAID & /etc/fstab, I think the universal nature of the Ubuntu kernel will take care of the rest."

"The main thing is the disk controller drivers in the initrd. If you can work out what modules are required, add them to /etc/initramfs-tools/modules, run update-initramfs -kall -u before moving the hard drives to the new computer and it should just work ™. To work out what modules are required, boot a Live CD (or USB) and run lsmod|grep ata and look for ones like sata_via or pata_sis that match the chipset on your motherboard. Or, if it has a BIOS option to use AHCI, use the ahci module as it'll perform better.

RAID and fstab: RAID should be fine, as by default all partitions will be scanned for the MD signature, and Ubuntu has been using UUIDs in fstab for ages."