How can I do a Cache Refresh in Google Chrome?

"Push F12 or Ctrl+Shift+J to ""Open Developer Tools"" on Windows (On Mac: Cmd+Opt+I) then you can right click on the refresh icon and select 'Empty Cache and Hard Reload'

See: stackoverflow.com/questions/12633425/chrome-browser-reload-options-new-feature

The documentation says:

For Windows and Linux: Shift+F5 or Ctrl+Shift+R

(screenshot):

For Mac: Cmd+Shft+R):

Reloads your current page, ignoring cached content.

Although some have reported this works, others have said it does not work correctly

Your other options are:

JavaScript Console

The JavaScript Console is available in two modes within Chrome DevTools: the primary Console tab, or as a split-view you can display while on another tab (such as Elements or Sources).

To open the Console tab, do one of the following:

Use the keyboard shortcut Command - Option - J (Mac) or Control -Shift -J (Windows/Linux).
Select View > Developer > JavaScript Console.

F12 doesn't appear to be mentioned here but will open this console on Windows as well.

Chrome Developer Tools

Using the JavaScript Console
Incognito window

Another interesting option is to open a new incognito window (Ctrl+Shift+N On Mac: ⌘ + Shift + N.). This window won't use any stored cookies, cached content, or DNS resolutions, so you can test stuff in it without slowing your normal browsing down by dumping the cache. This is what I almost always do instead of clearing the cache. support.google.com/chrome/answer/95464
Disable cache

Open Chrome Developer Tools (F12, Mac: ⌘+⌥+I). Click the settings icon (a gear in the bottom right corner). Check ""Disable cache"". Now when you browse with your Developer tools open caching is disabled.
Click&Clean

Finally there is also the option of the Click&Clean extension"

"According to documentation, Ctrl+F5 or Shift+F5 should work.
Maybe you have a proxy configured on IE & chrome, which is caching your page?"

Chrome sucks for this. Sometimes I can get Shift+F5 to work but not always. My solution for the moment is to use the 'Click & Clean' extension. It's ugly but works every time so I'd recommend that for now.

Open Chrome Developer Tools (F12 or Ctrl+Shift+I or Menu/Tools/Developer Tools). Click the settings icon (a gear in the bottom right corner). Check "Disable cache". Now when you browse with your Developer tools open caching is disabled.

You can right click, go Inspect Element under the Resources or Application (in newer versions) tab collapse Cookies right click on domain name and click Clear.