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Aluminum Exposure and Alzheimer's Disease

Aluminum Exposure and Alzheimer's Disease
"""What is the disease Alzheimer's?

The most prevalent cause of senile brain disease is Alzheimer's Disease (AD). It starts with memory deficiencies and develops to include all facets of intellectual function, such as judgment, computation, and language.

Does Alzheimer's disease result from aluminum exposure?

There is debate regarding whether aluminum can lead to Alzheimer's. The majority of people with Alzheimer's disease had higher-than-normal levels of aluminum in their brains, according to post-mortem studies of the patients. Normal healthy brain tissue does not contain aluminum, and scientists are unsure of how or why the metal builds up in the brain. It is yet unknown if aluminum contributes to or slows the development of Alzheimer's disease. Aluminum is known to be harmful to animal neurons, and it probably has a similar effect on the nerve cells and brain tissue in humans. Early studies on animal models revealed a connection between aluminum exposure and Alzheimer's disease. Testing animals' brains were given injections of aluminum salts, which led to alterations identical to those seen in patients' brains. In conclusion, it is still unknown what causes Alzheimer's disease and whether aluminum is involved. Findings have been contradictory. The following are listed by the Alzheimer Society of Canada as risk factors for dementia, which includes Alzheimer's disease: Age genetics of gender elevated blood pressure Smoking Diabetes obesity and a lack of exercise bad diet excessive alcoholic beverage use Low levels of mental activity Depression harm to the brain from trauma air toxicity

What are the sources of exposure to aluminum?

When aluminum and its alloys are produced, processed, or used, workers may be exposed to aluminum. People can come into touch with aluminum in a variety of additional ways besides working exposure. Aluminum can be present in various medicines, food, and water. It would be challenging to avoid this exposure, according to the Alzheimer Society of Canada, even though eating aluminum from cookware and other products is thought to constitute a relatively minor portion of the average person's consumption of the metal.

When working with aluminum, are there any exposure restrictions?

Based on respirable particle size, the American Conference of Governmental Industrial Hygienists (ACGIH) has established an occupational exposure limit. The suggested Threshold Limit Value Time-Weighted Average (TLV-TWA) exposure limit for aluminum in the air for 2022 by the ACGIH is 1 mg/m3 for both insoluble compounds and aluminum metal (CAS number 7429-90-5). The ACGIH additionally classifies aluminum metal and insoluble substances with respirable particle sizes as A4 - Not classifiable as a Human Carcinogen; agents that raise questions about their potential to cause cancer in people but that cannot be determined with certainty due to a lack of data. The time-weighted average airborne concentration (TLV-TWA) for a typical 8-hour workday and 40-hour workweek is the level to which it is thought that almost all employees can be continuously exposed, day after day, without suffering negative health consequences. Exposure limits in several Canadian jurisdictions are identical to or comparable to the ACGIH TLVs. The proper government agency in each jurisdiction should be consulted because there can be differences in how exposure limits are set, understood, and put into practice."""
 

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"Aluminum Exposure and Alzheimer's Disease" was written by Mary under the Health category. It has been read 23 times and generated 0 comments. The article was created on and updated on 15 January 2023.
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