Any Suggested Maintenance for Cloned Mac OS X Boot Disk

"If the cloning process succeeded, you can boot from the new drive, and Spotlight (and Time Machine if you're using it) work fine, there should be nothing that you need to clean up from the process.

Screw ups in a copy will either be catastrophic and you'd notice immediately, or minor (like corruption of a document) that you won't notice unless you open and verify just about every file on the hard drive.

If you've used the new drive for a couple of days and the system isn't acting strangely, I'd say you're good to go."