Super key to pause, mute mic, and mute speakers in windows

"#z::
soundget, isMute, MICROPHONE, MUTE
if isMute = Off
toMute = 1
else
toMute=0
SoundSet, toMute, MICROPHONE, MUTE
return

Would toggle the mic's muted state on win&z. Muting master volume would be much the same, except instead of MICROPHONE you would put MASTER, however if it's just your media player you want muting it may be better to set up a hotkey to pause it, rather than mute system volume. Depending on the player it may be able to do it itself, otherwise look into the ControlSend function.

(This has the advantage of not using NirCMD, as while it's a brilliant tool, the ~.5 second disk lag is really annoying to me :()"

"you can do this and much more by using NirCMD along with AutoHotKey.

Take a look: http://www.nirsoft.net/utils/nircmd.html

NirCmd is a small command-line utility
that allows you to do some useful
tasks without displaying any user
interface. By running NirCmd with
simple command-line option, you can
write and delete values and keys in
the Registry, write values into INI
file, dial to your internet account or
connect to a VPN network, restart
windows or shut down the computer,
create shortcut to a file, change the
created/modified date of a file,
change your display settings, turn off
your monitor, open the door of your
CD-ROM drive, and more..."

"A microphone muting utility:
http://oelgaard.dk/torkils/?TorkilsMicMuter
Shortcut key is configurable as is the signalling of the current mute state:

Semitransparent corner notifications on all monitors of current mute state. If a corner notification is ""in the way"" during an online meeting, then the notification can easily be removed by hovering the mouse over it."

"I have set ctrl+p to toggle the system sound, for window+z it would be:

#z::Send {Volume_Mute}"

"Here is a sample AutoHotKey command to use nircmd to mute a mic. You will have to play around with the number at the end, it refers to mic number.

#z:: Run c:\tools\nircmd\nircmd.exe mutesysvolume 2 microphone 2

Press Windows + Z to toggle mute."