How do I reduce the size of a huge MP4 video?

How do I reduce the size of a huge MP4 video? I have a 4GB MP4 video file that I shot with the HD Flip Mino. How do I reduce it to no more than 1GB without losing too much quality?
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bert [Entry]

"Use ""HandBrake"". Import the file. Select ""High Profile"" and then click on ""Start"". It can compress 100 MB file to 27 MB or more. (Input file must not be in a already compressed state). If you use Handbrake version 0.9.5 then there is a setting to input File Size you want to compress in. (Upper version of HB does not have this feature).

Sorenson Squeeze is another professional Level tool for this kind of job."