How do you create a bootable partition on a USB drive?

How do you create a bootable partition on a USB drive? I have a bootable ISO designed to be burned to a double-layer DVD. I don't have a double layer DVD burner, so I would like to stick the ISO image on a 50 GB partition on a USB hard drive I have. How do I get the boot info onto the hard drive?
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bert [Entry]

I've had success using WinGrub on a machine that only had net access. (No bootable usb, broken cd drive.) The site has changed since then: gnadotorg/projects/grub4dos/. I don't have the details any more, but I was able to boot GParted off of a USB key on that old broken machine. You can also use it to boot ISO images. You may not even need WinGrub if you have GRUB on your machine already.